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Geochemistry is at the core of most of Dan’s research. Much of his work combines novel analytical approaches with geochemical modeling. Dan pioneered the use of atomic absorption spectroscopy to measure minor and trace elements (Sr/Ca ratios and Mg/Ca ratios) in biological carbonates (corals, foraminifera) precisely enough to reconstruct sea surface temperatures over a variety of timescales. With former postdoc Mike Evans, he developed the use of oxygen isotope measurements in cellulose to reconstruct seasonal cycles in tropical trees that lack visible annual rings. More recently, he has worked with former students Kate Dennis and Sierra Petersen to improve the clumped isotope measurements, decreasing sample size requirements. Many students have worked with Dan to develop new measurement techniques including Sasha Turchyn (oxygen isotopes in sulfate) and John Higgins (Mg isotopes in carbonates). In almost every case, novel analytical approaches are combined with a quantitative framework for understanding chemical transport and reaction, as well as biogeochemical cycling, for example his work with former student Julie Shoemaker on understanding methanogenesis in terrestrial wetlands.